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While UM can arise from melanocytes anywhere in the uveal tract, it most commonly occurs in the choroid.2
Other, less common primary intraocular malignancies include vitreoretinal lymphoma and retinoblastoma.4
Please download the brochure for more information on uveal melanoma.
DownloadPreexisting medical conditions such as congenital ocular melanocytosis, melanocytoma, neurofibromatosis, and ocular nevi (benign melanocytic lesions that can rarely develop into melanomas).2,9,13
“I was fitted for the contacts, and afterward, during the eye exam, the ophthalmologist said, ‘There’s a shadow in the back of your left eye. May I dilate your eye?’ He came back and said, ‘I’ve scheduled an appointment for you to see a specialist . . . I was hoping I wouldn’t need to tell you this, but this may be a matter of life and death. I’m very serious—you need to keep this eye appointment.’”—Patient with UM
Click below to see how patients may experience symptoms of UM. If your patients are experiencing these symptoms, a closer investigation may be warranted.
Watch Bertil Damato, MD, PhD, discuss the importance of systematic examinations.
Play videoIn addition to growth of lesions, ophthalmologists pay especially close attention to other attributes when distinguishing small melanomas from benign lesions, including19:
Enucleation (removal of the eye) does not seem to improve survival compared with brachytherapy (focal delivery of radiation to the tumor). Therefore, treatment for primary disease has focused on vision- and eye-preserving techniques.10
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